Carmax and Medtronic are big market movers

NEW YORK (AP) — Stocks that moved substantially or traded heavily Tuesday on the New York Stock Exchange and the Nasdaq Stock Market:

NYSE

Carmax Inc., down $5.01 to $47.80

The used car retailer reported a boost in quarterly profit, but the results fell short of Wall Street expectations.

Medtronic Inc., down $1.90 to $64.08

New regulations could make the medical device maker's buyout of Ireland-based Covidien for tax purposes more difficult to complete.

Peabody Energy Corp., up 21 cents to $12.86

The coal mine operator raised its third-quarter financial outlook, partly citing higher-than-expected results from the western U.S.

Spectrum Brands Holdings Inc., up $2.43 to $88.56

The consumer products company is buying Procter & Gamble's pet care business, including Iams brands, in 42 European markets.

CF Industries Holdings Inc., up $13.59 to $269.37

The fertilizer products company is in preliminary discussions with Norway's Yara International about a possible merger deal.

Millennial Media Inc., up 30 cents to $2.07

The mobile advertising technology company said it will buy privately held Nexage for $107.5 million in a cash and stock deal.

Nasdaq

Ascena Retail Group Inc., down $2.78 to $13.75

The retail group reported a decline in quarterly profit and sales at established stores, and issued financial guidance below expectations.

Salix Pharmaceuticals Ltd., up $9.34 to $169.17

Allergan Inc. has revived discussions to buy the drug developer and medical device maker, according to multiple media reports.